3 Microplate Manufacturers in 2024
This section provides an overview for microplates as well as their applications and principles. Also, please take a look at the list of 3 microplate manufacturers and their company rankings.
Table of Contents
What Is a Microplate?
A microplate, sometimes called a microtiter plate, is a laboratory tool used primarily in biochemical experiments. It consists of multiple transparent wells, functioning similarly to small petri dishes. The design of the wells, including their shape, color, volume, surface material, and coating, varies according to the intended use.
Uses of Microplate
Microplates enable simultaneous experiments across many wells, making them ideal for collecting large amounts of data under consistent conditions. They are used in cell line and microorganism culturing, dilution series measurement, and with microplate readers for absorption and fluorescence detection. Common applications include ELISA (enzyme-linked immunosorbent assay) in biochemistry and clinical testing, and high throughput screening (HTS) in drug discovery. They are also used for direct sample observation under a microscope or for cellular imaging.
Principle of Microplate
Microplates are coated with various materials to facilitate sample adsorption and immobilization. ELISA, involving highly specific antigen-antibody reactions, is a common use. In ELISA, antibodies bind to antigens on the microplate, with the luminescence from an enzyme reaction detectable by a microplate reader. This method allows for the quantitative measurement of trace samples with high sensitivity and without radiation exposure.
Types of Microplate
1. Classification by the Number and Size of Wells
Microplates vary from the standard 96-well plate to versions with 6 to 9,600 wells. The well size inversely correlates with the number of wells.
2. Classification by Well Shape
Wells can be flat-bottomed, round-bottomed, or V-bottomed, each suited for specific applications, such as bottom-reading plate readers, cell culture, or sample collection.
3. Classification by Plate Material
Common materials include polystyrene, polypropylene, and glass, each offering different chemical resistance.
4. Surface Treatment
The non-surface-treated polystyrene surface is hydrophobic and can interact with and immobilize biomolecules with hydrophobic portions, such as antibodies. Some have high-binding surface coatings that enhance binding to hydrophobic molecules, while others have hydrophilic surface (polyethylene oxide-like) coatings to minimize intermolecular interactions.
Others have surface-coated molecular structures (e.g., maleimide or hydroxy groups) that covalently bind to and immobilize specific functional groups of the sample, allowing them to orient and immobilize specific biomolecules.
5. Color
While transparent is standard, black and white plates are used to reduce light scattering in fluorescence and enhance signal-to-noise ratio in luminescence detection, respectively.
List of 3 Microplate Manufacturers
*Including some distributors, etc.
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- Company Size: largest first
- Year Founded: oldest first
- Year Founded: earliest first
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- United States of America
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Thermo Fisher Scientific Inc.
polypropylene plates
Company Overview
Thermo Fisher Scientific Inc., founded in 1956 and headquartered in Waltham, Massachusetts, is a manufacturer and supplier of life science solutions, analytical instruments, specialty diagnostics, laboratory products, and biopharma services. Through its brand names, including Invitrogen, Fisher Scientific, Patheon, Applied Biosystems, and Gibco, among others, the company provides a wide range of products, which include chromatography systems, thermal cyclers, automated cell counters, fermenters, and DNA polymerases. The company’s annual revenue is over 40 billion USD, and it serves several fields, including customers working in clinical diagnostic labs, research institutions, hospitals, government agencies, and pharmaceutical/biotech companies.
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BrandTech Scientific, Inc.
Microplates
Company Overview
BrandTech Scientific was founded in 1996 and is headquartered in Essex, Connecticut. BrandTech Scientific supports laboratory sciences as a distributor for German-made supplies in Canada and the United States. BrandTech Scientific’s products include categories such as liquid handling including pipettes and instrumentation, life science such as PCR products and microplates, laboratory vacuum such as rotary vein pumps, lab support jacks, lab ware such as test tube racks, volumetric lab ware hardware and software, and lab rat gear, as well as offering vacuum pump selection guides.
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Hirschmann Laborgeräte GmbH & Co. KG
MICROPLATES
Manufacturer Overview
Hirschmann Laborgeräte GmbH & Co. KG, established in 1964 and headquartered in Eberstadt, Germany, is a manufacturer of laboratory instruments, volumetric analysis glass instruments, and precision capillaries. The company offers a range of products, including peristaltic pumps, liquid handling systems, volumetric instruments, and precision capillaries. It also offers volumetric measuring, hematocrit capillaries, counting chambers, and syringe filters. Its peristaltic pumps offer high chemical resistance and are suitable for use with aggressive, corrosive, and viscous media. Additionally, the company has achieved ISO 9001:2015 certifications. It serves various industries, including pharmaceuticals, chemicals, food and beverage, and environmental analysis.
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Microplate Manufacturer Ranking
*Including some distributors, etc.Number of Employees
Newly Established Company
- Hirschmann Laborgeräte GmbH & Co. KG: 1964 (60 years ago)
Company with a History
- Hirschmann Laborgeräte GmbH & Co. KG: 1964 (60 years ago)
Microplate Manufacturers in United States
*Including some distributors, etc.
Global Distribution of Microplate Manufacturers by Country
*Including some distributors, etc.
| Country | Number of Companies | Share (%) |
|---|---|---|
United States of America
|
2 | 100.0% |
